EFFECTS OF PHYSICAL EXERCISES ON TRIACYLGLYCEROL LEVEL IN SKELETAL MUSCLES IN DIETARY-INDUCED OBESE RATS-Reference-Cited by-同舟云学术

EFFECTS OF PHYSICAL EXERCISES ON TRIACYLGLYCEROL LEVEL IN SKELETAL MUSCLES IN DIETARY-INDUCED OBESE RATS

Published:2014-02-28 Issue:1 Volume:13 Page:92-97
ISSN:1819-3684
Container-title:Bulletin of Siberian Medicine
language:
Short-container-title:Bûll. sib. med.

Author:

Yakimovich I. Yu.¹,Borodin D. A.¹,Podrezov I. K.¹,Ivanov V. V.¹,Vasiliyev V. N.¹,Kotlovsky M. Yu.²

Affiliation:

1. Siberian State Medical University, Tomsk

2. Krasnoyarsk State Medical University, Krasnoyarsk

Abstract

The accumulation of triacylglycerol in peripheral tissues is one of mechanisms of insulin resistance. This paper presents the investigation of the influence of aerobic and anaerobic physical exercises on triacylglycerol level in skeletal muscles and on insulin resistance in dietary-induced obese rats. It is estimated that a high-energy (HE) diet causes the accumulation of triacylglycerols in skeletal muscles that leads to high resistance to insulin. Aerobic and anaerobic physical exercises reduce the level of triacylglycerols in skeletal muscles and raise sensitivity to insulin in obese rats. Physical exercises raise the level of triacylglycerols in skeletal muscles in standard-diet rats that probably is the adaptation to high energy expenditure, but does not lead to high insulin resistance.

Publisher

Siberian State Medical University

Subject

Molecular Medicine

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