MITOCHONDRIAL PROTEIN PROFILE AND ITS ROLE IN PATHOLOGIC PROCESSES-Reference-Cited by-同舟云学术

MITOCHONDRIAL PROTEIN PROFILE AND ITS ROLE IN PATHOLOGIC PROCESSES

Published:2013-06-28 Issue:3 Volume:12 Page:5-17
ISSN:1819-3684
Container-title:Bulletin of Siberian Medicine
language:
Short-container-title:Bûll. sib. med.

Author:

Kosterina Ye. A.¹,Kozenkov I. I.¹,Kasymov V. A.¹,Kamensky P. A.¹,Dominova I. N.¹,Korolyova Yu. A.¹,Patrusheva V. Ye.¹,Bogachev R. S.¹,Litvinova L. S.¹,Babak S. V.¹,Moiseeva Ye. M.¹,Bogdanov Ye. A.¹,Mukhortova O. A.¹,Vavilina Ya. S.¹,Mikhalchenkova T. A.¹,Patrushev M. V.¹

Affiliation:

1. Immanuel Kant Baltic Federal University, Kaliningrad

Abstract

Mitochondria import hundreds of different precursor proteins from the cytosol, and only 13 proteins are encoded by mtDNA itself. Recent investigations demonstrated real size of mitochondrial proteome and complexity of their functions There are many methods using for mitochondrial proteome profiling, that help to understand a molecular mechanisms of mitochondrial functions and identify the causes of disruptions that lead to different disorders. In this review we discuss a recent data in the field of mitochondrial proteomics.

Publisher

Siberian State Medical University

Subject

Molecular Medicine

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