THE RHEOLOGICAL PROPERTIES OF BLOOD IN THE MOST ACUTE STAGE OF ISCHEMIC STROKE AND THEIR RELATION TO THE SEVERITY OF NEUROLOGICAL IMPAIRMENT-Reference-Cited by-同舟云学术

THE RHEOLOGICAL PROPERTIES OF BLOOD IN THE MOST ACUTE STAGE OF ISCHEMIC STROKE AND THEIR RELATION TO THE SEVERITY OF NEUROLOGICAL IMPAIRMENT

Published:2013-10-28 Issue:5 Volume:12 Page:5-12
ISSN:1819-3684
Container-title:Bulletin of Siberian Medicine
language:
Short-container-title:Bûll. sib. med.

Author:

Azhermacheva M. N.¹,Plotnikov D. M.¹,Aliev O. I.²,Alifirova V. M.¹,Plotnikov M. B.²,Burkova K. I.³

Affiliation:

1. Siberian State Medical University, Tomsk

2. Institute of Pharmacology, SB of Russian Academy of Medical Sciences, Tomsk

3. Regional Vascular Center, Tomsk

Abstract

The study evaluated the rheological parameters of blood: blood viscosity, plasma viscosity, hematocrit, red blood cell aggregation and deformability. The severity of the patients was assessed by clinical scales:Glasgowcoma scale, the scale NIHSS, Barthel index. The study found that in the acute phase of ischemic stroke increased blood viscosity by increasing red blood cell aggregation and reduced erythrocyte deformability. The increase in the viscosity of the blood in acute ischemic stroke is accompanied by increased severity of neurological disorders.

Publisher

Siberian State Medical University

Subject

Molecular Medicine

Reference33 articles.

1. Lozano R., Naghavi M., Foreman K. et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. The Lancet, 2013, vol. 380, issue 9859, pp. 2095–2128.

2. Johnston S.C., Mendis S., Mathers C.D. Global variati on in stroke burden and mortality: estimates from monito ring, surveillance, and modeling. Lancet Neurol., 2009, pp. 56–59.

3. Plotnikov M.B., Aliev O.I., Plotnikova T.M. Methodological approaches to the study of substances that affect the rheology. Eksperimental'naya i klinicheskaya farmakologiya, 2011, vol. 74, no. 12, pp. 36–39 (in Russian).

4. Smertina E.G.,Prokopenko S.V., Ionova V.G., Tanashyan M.M., Potylitsina V.V. Bulletin of Siberian Medicine, 2009, no. 1 (2), pp. 72–78 (in Russian).

5. GBD 2010 Country Collaboration: GBD 2010 country results: a global public good. The Lancet, 2013, vol. 381, issue 9871, pp. 965–970.