Remodeling of the common carotid artery in oncohematological pathology by ultrasound

Author:

Koptev V. D.1,Nimaev V. V.2,Gorchakov V. N.3

Affiliation:

1. National Research Novosibirsk State University (NRNSU)

2. Institute of Clinical and Experimental Lymphology (ICEL)

3. National Research Novosibirsk State University (NRNSU); Institute of Clinical and Experimental Lymphology (ICEL)

Abstract

The aimis the assessment of structural and functional state of common carotid artery by ultrasound in patients with non-Hodgkin malignant lymphomas (NHML) before and after chemotherapy.Materials and methods.The common carotid artery of 111 patients at different stages of NHML were examined via a “LOGIC 400” ultrasound.Results.The common carotid artery of patients with NHML is undergoing morphological modification with changes in thickness and diameter, which corresponds to a hypertrophic type of remodeling. There is an increase in the thickness of the complex “intima-media” and Kernogan`s index with decreasing the common carotid artery diameter by comparison with the control group. Chemotherapy improves the parameters of the common carotid artery while reducing the thickness of the complex “intima-media” and Kernogan`s index at different stages of NHML.Conclusion.Remodeling of the common carotid artery is associated with the developmental stage of NHML. Chemotherapy leads to an improvement of the morphological parameters of the common carotid artery, which evaluates the effect of the treatment.

Publisher

Siberian State Medical University

Subject

Molecular Medicine

Reference24 articles.

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4. Koptev V.D., Gorchakov V.N., Pospelova T.I. Intrarenal parenchymal blood flow in patients with non-Hodgkin’s malignant lymphomas at different stages of disease development. Sovremennye problemy nauki i obrazovanija – Modern Рroblems of Sience and Еducation. 2015; 3: URL: https://scienceeducation.ru/ru/article/view?id=20203 (reference date: 29.04.2015) (in Russ.)

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