Dithizone injuring action to blood granulocytes and basal parts of intestine crypts-Reference-Cited by-同舟云学术

Dithizone injuring action to blood granulocytes and basal parts of intestine crypts

Published:2010-10-28 Issue:5 Volume:9 Page:24-27
ISSN:1819-3684
Container-title:Bulletin of Siberian Medicine
language:
Short-container-title:Bûll. sib. med.

Author:

Yeschenko Yu. V.,Novitsky V. V.,Bovt V. D.,Yeschenko V. A.,Urazova O. I.,Grigorova N. V.

Abstract

It was shown, that dithizone injection to rats induced zinc deficiency in blood granulocytes and Paneth cells. Phase changes of zinc content were observed in the cells. First phase (primary decrease of cytochemically detected zinc content in the cells) was a result of intravital binding of this metal to dithizone. Second one (permanent partial increase of cell zinc content) was a result of decomposition of the product of intravital reaction. Third phase (secondary decrease of cell zinc concentration) was connected with cell necrosis. Dithizone injection to animals also induced cell secretory material deficiency.

Publisher

Siberian State Medical University

Subject

Molecular Medicine

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