INFLUENCE OF MAGNETOMICELLS BASED ON IRON NANOPARTICLES COATED BY CARBON ON STRUCTURE OF RAT LIVER-Reference-Cited by-同舟云学术

INFLUENCE OF MAGNETOMICELLS BASED ON IRON NANOPARTICLES COATED BY CARBON ON STRUCTURE OF RAT LIVER

Published:2015-04-28 Issue:2 Volume:14 Page:5-11
ISSN:1819-3684
Container-title:Bulletin of Siberian Medicine
language:
Short-container-title:Bûll. sib. med.

Author:

Vasyukov G. Yu.¹,Milto I. V.²,Sukhodolo I. V.³,Mitrofanova I. V.³

Affiliation:

1. Siberian State Medical University, Tomsk; Institute of Complex Problems of Cardio-Vascular Diseases, Kemerovo

2. Siberian State Medical University, Tomsk; National Research Tomsk Polytechnic University, Tomsk

3. Siberian State Medical University, Tomsk

Abstract

In this paper we study the effect of a single intravenous injection of suspension of magnitomitsell based on iron nanoparticles modified with carbon on the structure of the rat liver. Histological examination revealed the hemodynamic disturbances in the stroma of the organ and degenerative changes of hepatocytes from 1 to 40 days of the experiment. Perls histochemical reaction demonstrated the accumulation of modified iron nanoparticles in cells of the mononuclear phagocyte system of the liver. Number of Perlspositive macrophages decreased during the experiment from 1 to 40 per day.

Publisher

Siberian State Medical University

Subject

Molecular Medicine

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