The Emerging Relationship Between Regenerative Medicine and Physical Therapeutics

Author:

Ambrosio Fabrisia1,Wolf Steven L.2,Delitto Anthony3,Fitzgerald G. Kelley4,Badylak Stephen F.5,Boninger Michael L.6,Russell Alan J.7

Affiliation:

1. F. Ambrosio, PT, PhD, MPT, is Director, Cellular Rehabilitation Laboratory, W1453 Biomedical Science Tower, 200 Lothrop St, Pittsburgh, PA 15213 (USA), and Assistant Professor, Departments of Physical Medicine and Rehabilitation, Physical Therapy, and Orthopedic Surgery and McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.

2. S.L. Wolf, PT, PhD, FAPTA, FAHA, is Professor, Division of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, Georgia.

3. A. Delitto, PT, PhD, FAPTA, is Professor and Chair, Department of Physical Therapy, University of Pittsburgh.

4. G.K. Fitzgerald, PT, PhD, OCS, FAPTA, is Associate Professor, Department of Physical Therapy, University of Pittsburgh.

5. S.F. Badylak, DVM, PhD, MD, is Professor, McGowan Institute for Regenerative Medicine and Department of Surgery, University of Pittsburgh.

6. M.L. Boninger, MD, is Professor and Chair, Department of Physical Medicine and Rehabilitation and McGowan Institute for Regenerative Medicine, University of Pittsburgh.

7. A.J. Russell, PhD, is Distinguished Professor, McGowan Institute for Regenerative Medicine and Department of Surgery, University of Pittsburgh.

Abstract

Dramatic changes in the health care landscape over the next few decades undoubtedly will affect rehabilitation specialists' practice. In the multidisciplinary field of regenerative medicine, cell, tissue, or organ substitutes are used to enhance the healing potential of the body. Given that the restoration of normal functioning of injured or diseased tissues is expected to be the ultimate goal of these therapies, the future of regenerative medicine is, undeniably, tightly intertwined with that of rehabilitation. Rehabilitation specialists not only must be aware of cutting-edge medical advances as they relate to regenerative medicine but also must work closely with basic scientists to guide the development of clinically relevant protocols. The purposes of this article are to provide a current perspective on biological approaches to the management of musculoskeletal disorders and to highlight the needed integration of physical therapeutics with regenerative medicine.

Publisher

Oxford University Press (OUP)

Subject

Physical Therapy, Sports Therapy and Rehabilitation

Reference64 articles.

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4. Development of biomaterial scaffold for nerve tissue engineering: biomaterial mediated neural regeneration;Subramanian;J Biomed Sci,2009

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