Determination of HNP and pKa Values of Some 3-Alkyl(Aryl)-4-phthalimido-4,5-dihydro-1H-1,2,4-triazol-5-one Compounds by Semi-Neutralization Method-Reference-Cited by-同舟云学术

Determination of HNP and pKa Values of Some 3-Alkyl(Aryl)-4-phthalimido-4,5-dihydro-1H-1,2,4-triazol-5-one Compounds by Semi-Neutralization Method

Published:2022-12-21 Issue: Volume: Page:
ISSN:2148-6840
Container-title:Caucasian Journal of Science
language:en
Short-container-title:Caucasian J. Sci.

Author:

YÜKSEK Haydar¹,MANAP Sevda¹^ORCID,ÖZDEMİR Gül²

Affiliation:

1. KAFKAS UNIVERSITY

2. KAFKAS ÜNİVERSİTESİ, FEN-EDEBİYAT FAKÜLTESİ

Abstract

In this study, the effects of solvents and molecular structure upon acidity, five 3-alkyl(aryl)-4-phthalimido-4,5-dihydro-1H-1,2,4-triazol-5-ones (3-7) were potentiometrically titrated with tetrabutylammonium hydroxide (TBAH) in four different anhydrous solvents (isopropyl alcohol, acetonitrile, tert-butyl alcohol and N,N-dimethylformamide) and HNP and corresponding pKa values were determined by half-neutralization method for all cases.

Publisher

Caucasian Journal of Science

Subject

General Medicine

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