Diagnosis and Therapeutic Management of Canine Demodicosis in Saurashtra Region of Gujarat
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Published:2022-09-15
Issue:4
Volume:18
Page:139-142
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ISSN:2395-1176
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Container-title:Indian Journal of Veterinary Sciences & Biotechnology
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language:
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Short-container-title:ijvsbt
Author:
Satasiya Chintan G.,Vagh Arshi A.,Bilwal Awinash K.,Bhatt Raghuvir H.,Parasana Dixit K.
Abstract
Among 23 dogs positive with canine demodicosis, 18 were selected for study, and 6 healthy dogs were taken as control. The dogs were divided into 4 groups, each consisting of 6 animals. Group I served as control. Group II, III and IV were treatment groups. Dogs of group II were given a subcutaneous injection of ivermectin @ 0.2 mg/kg b.wt weekly up to 4 weeks in combination with topical application of amitraz 12.5% solution as 0.05% mixed in water. Dogs of group III were given safrone tablets PO for 10 days in combination with safrone oil topically for 15 days. Dogs of group IV were given a fluralaner tablet @ 25 mg/kg PO for a single dose. All the dogs were bathed with shampoo containing benzoyl peroxide at weekly interval, except dogs of group III, and were given cefpodoximeproxetil @ 10 mg/kg b.wt. and pheniramine maleate @ 1 mg/kg b.wt. PO bid for 5 days and vitabestderm syrup 5 mL PO bid. Serum interleukin (IL)-10 showed a significant or appreciable increase in demodectic animals compared to healthy animals. Mite count was reduced up to 100 % on 30th day post-treatment in dogs of group II and there was quite a reduction in mite count in dogs of group IV, while lowest reduction in mite count was noticed 30th day post-treatment in dogs of group III. So, it was concluded that a combination of injection of ivermectin subcutaneously and amitraz 12.5% solution diluted to 0.05% topically had the highest efficacy among 3 treatment protocols used for canine demodicosis.
Reference18 articles.
1. Beugnet, F., Halos, L., Larsen, D., & de Vos, C. (2016). Efficacy of oral afoxolaner for the treatment of canine generalised demodicosis. Parasite, 23, 14. 2. Chaudhary, S., Murlidhara, A., Upendra H.A., & Ravindranath B. M. (2011). Treatment of amitraz-resistant Juvenile generalized demodicosis in dogs. Intas Polivet , 12(1), 78-79. 3. Djuric, M., Matic N.M., Davitkov, D., Glavinic, U., Davitkov, D., Vejnovic, B., & Stanimirovic, Z. (2019). Efficacy of oral furalaner for the treatment of canine generalized demodicosis: a molecular-level confirmation. Parasites & Vectors, 12(1), 1-6. 4. Duangkaew, L., Larsuprom, L., Anukkul, P., Lekcharoensuk, C., & Chen, C. (2018). A field trial in Thailand of the efficacy of oral fluralaner for the treatment of dogs with generalized demodicosis. Veterinary Dermatology, 29(3), 1-6. 5. Ettinger, S.J., & Feldmen, E.C. (2017). Textbook of Veterinary Internal Medicine. 8th ed. St. Louis. Elsevier Saunders. pp 980-989. Felix, A.O.C., Guiot, E.G., Stein, M. Felix, S.R., Silva, E.F., & Nobre, M.O. (2013). Comparison of systemic interleukin 10 concentrations in healthy dogs and those suffering from recurring and first time Demodexcanis infestations. Veterinary Parasitology, 193, 312-315.
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