Effect of Uterine Lavage, Levamisole, PGF2α and its Combinations on Haematological Indices and Bacterial Load in Estrual Mucus of Endometritic Buffaloes

Abstract

The objective of this study was to compare uterine lavage, Levamisol s/c, PGF2α i/m and its combinations on haematological indices, bacterial load in cervico-vaginal mucus (CVM) and therapeutic response in endometritic buffaloes. Thirty six repeat breeder buffaloes were randomly assigned into six equal groups. Six animals were kept as positive control (no treatment, only sexual rest, T0 ), and the rests were assigned to five treatment group, i.e., T1 (uterine lavage), T2 (Levamisol SQ ), T3 (PGF2α IM ), T4 (uterine lavage plus Levamisol s/c) and T5 (uterine lavage plus PGF2α  IM ). Significant (p<0.05) decline in bacterial load and TLC values were recorded after treatment over pretreatment ones in all five treatment groups. Furthermore, Hb, TEC and PCV increased significantly after treatment as compared to control one. Significant drop in neutrophils and rise in lymphocytes was recorded post-treatment in all treatment groups. The eosinophil, basophil and monocytes did not differ significantly within and amongst the groups. The therapeutic response was 33.33, 50.00, 66.67, 66.67, 83.33 and 83.33% in T0, T1, T2, T3, T4 and T5, respectively. The corresponding conception rates were 16.67, 33.33, 50.00, 50.00, 66.67 and 66.67 %. The results conclude that, uterine lavage along with Levamisol or PGF2α can be used effectively to manage endometrtitic buffaloes.