The Correlation between Changes in Serum Sodium and Hospital Mortality in Critically Ill Children with Acute Kidney Injury

Abstract

For critically ill patients with acute kidney injury (AKI), early warning and intervention can be achieved through monitoring serum sodium levels. However, the normal range of serum sodium levels in AKI patients in the intensive care unit (ICU) is not yet clear. This article aims to use statistical methods to study the relationship between changes in serum sodium and hospital mortality in critically ill children with acute kidney injury. This article conducted a retrospective observational cohort study on multiple critically ill children with acute kidney injury using the China Large Pediatric Intensive Care Database to demonstrate that serum sodium levels as an independent predictor can be used to evaluate the hospital mortality rate of critically ill children with AKI. A total of 1505 eligible critically ill children with acute kidney injury were included in the study. The research results indicate that the normal range of serum sodium in children with AKI is approximately 135 to 142mmol/L. The increase or decrease in serum sodium concentration in critically ill children with acute kidney injury admitted to ICU is associated with in-hospital mortality. Therefore, in the ICU, it is necessary to continuously monitor and evaluate the serum sodium levels of children with acute kidney injury to prevent death due to the progression of the disease.