Analysis of variation of serum CEA, SCC, CYFRA21-1 in patients with lung cancer and their diagnostic value with EBUS-TBNA
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Published:2023-11-25
Issue:
Volume:
Page:
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ISSN:1452-8266
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Container-title:Journal of Medical Biochemistry
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language:
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Short-container-title:J Med Biochem
Author:
Du YanJia,Wen Ya,Huang JieYu
Abstract
Objective: To explore the variation of serum carcinoembryonic antigen (CEA), cytokeratin 19 fragment (CYFRA21-1) and squamous cell carcinoma (SCC) antigen in patients with lung cancer (LC) and their diagnostic value with endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA).
Methods: Selection of 150 patients with suspected lung malignant lesions as the research objects was to analyze the diagnostic value of serum tumor marker test and EBUS-TBNA joint detection for LC.
Results: The AUC of joint examination to diagnose LC and identify pathological types of LC was elevated vs. alone detection of each index.
Conclusions: Serum CYFRA21-1, SCC and CEA conjugating with EBUS-TBNA are provided with diagnostic value for LC and identified value for pathological types of LC.
Publisher
Centre for Evaluation in Education and Science (CEON/CEES)
Subject
Biochemistry (medical),Clinical Biochemistry