Author:
Hasković Edhem,Uzunalıć Harun,Unčanin Snežana,Herenda Safija,Hasković Denis,Selimović Amina
Abstract
Aim: The chief aim of this study was monitoring of laboratory parameters of chronic kidney failure in elderly patients. Methods: All samples were taken and processed by standard methods and according to the principles of good laboratory practice. Data were collected in an organized and systematic manner in the form of a questionnaire with respect to ethical principles and as such were analyzed by statistical tests and analyses (Student's t-test, Analysis of variance-ANOVA, Pearson's and Spearman's correlation coefficients). The limit of statistical significance was set at p < 0.05. Results: Mean values of creatinine clearance and proteinuria for the total study population were: 41.30 ± 21.43 mL/min, 1.5 ± 2.3 g/L/24 h, respectively. Hematological parameters did not significantly differ from normal values. The highest frequency of comorbidities was observed in subjects aged ≥ 80 years with an average of 2.03 comorbidities per subject. Serum creatinine and urea values as well as creatinine clearance are good indicators of disease progression. Conclusion: The results of the presented research suggest that old age is a predisposing risk factor for the development of chronic kidney disease, and that in combination with comorbidities (hypertension and/or diabetes), it contributes to poor prognosis or disease progression.
Publisher
Centre for Evaluation in Education and Science (CEON/CEES)
Reference20 articles.
1. United Nations, Department of Economic and Social Affairs, Population Division. World Population Prospects: The 2017 Revision, Key Findings and Advance Tables. New York, 2017. No. ESA/P/WP/248.;
2. Jurić I. Incidence of risk factors for the development of chronic renal failure in elderly patients. Dissertation, University of Zagreb, School of Medicine, Zagreb, Croatia, 2015.;
3. Duraković Z. Aging. Period Biol 2013; 115(4): 491-498.;
4. Parmar MS. Chronic renal disease. BMJ 2002; 325: 85-9. https://doi.org/10.1136/bmj.325.7355.85;
5. Stevens PE, Levin A. Kidney Disease: Improving Global Outcomes Chronic Kidney Disease Guideline Development Work Group Members. Evaluation and management of chronic kidney disease: synopsis of the kidney disease: improving global outcomes 2012 clinical practice guideline. Ann Intern Med 2013; 158 (11): 825-830. https://doi.org/10.7326/0003-4819-158-11-201306040-00007;