Acute myocardial infarction and diabetes mellitus

Author:

Gluvić Zoran,Kovačević Pejka,Obradović MilanORCID,Trebaljevac Jovana,Samardžić Vladimir,Lačković Milena,Isenović EsmaORCID

Abstract

Acute myocardial infarction (AMI) is a clinical form of coronary heart disease, which occurs after coronary arteries' occlusion and irreversible ischemia progression leads to myocardial necrosis. Morbidity and mortality caused by cardiovascular comorbidities, including AIM, are greater in patients with insulin - dependent diabetes than in non - diabetes patients of the same age. One of the reasons for a higher mortality rate from AMI in patients with diabetes may be heart failure. In addition, patients with diabetes and AMI have an increased risk for poor therapy outcomes of AMI compared with non - diabetes patients, and the main reasons are endothelial dysfunction, prothrombotic state, a greater possibility of restenosis, negative vascular remodelling, increased protein glycosylation, and vascular matrix deposition. In this review, we provide an overview of recent literature data and practical knowledge related to the AMI in diabetic patients.

Funder

Ministry of Education, Science and Technological Development of the Republic of Serbia

Publisher

Centre for Evaluation in Education and Science (CEON/CEES)

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