Factors associated with quality of life in patients with coronary artery disease before coronary artery bypass surgery

Abstract

Relevance. The outcomes of coronary artery bypass surgery (CABG) for coronary artery disease (CAD) depend on different factors, including patient’s quality of life (QoL) before CABG.Aim: To study QoL and associated factors in CAD patients before CABG.Material and Methods. A single-center observational study involved CAD patients who were admitted for elective CABG. All patients completed generic quality of life questionnaire SF-36 and specific questionnaire SAQ. Statistical methods included parametric and non-parametric comparisons and multiple regression analysis.Results. The study included 240 CAD patients (median age 65 years, males – 69%). More than half of the patients had poor physical and psychological health before CABG. Physical limitations and perception of the disease as well as role functioning were most impaired. QoL was worse in women, older patients, with obesity, comorbidity, long-lasting CAD, non-workers and living in sparsely populated areas (p < 0.05). Predictors of poor QoL – female gender (OR 2.574, 95% CI 1.335–4.961; p = 0.005), obesity (OR 1.984, 95% CI 1.075–3.663; p = 0.028) and long–term CAD (OR 1.006, 95% CI 1.002‒0.010; p = 0.006). Predictors of poor physical health – age ≥ 65 (OR 0,823, 95% CI 0.430–1.576; p = 0.001), obesity (OR 2,050, 95% CI 1.041–4.039; p = 0.038) and long–term CAD (OR 1.005, 95% CI 1.001–1.010; p = 0.027). Predictors of poor mental health – age ≥ 65 (OR 1.973, 95% CI 1.050–3.706; p = 0.035) and living in sparsely populated areas (OR 2.213, 95% CI 1.236–3.962; p = 0.008).Conclusion. Predictors of poor QoL before CABG are female gender, elderly age, obesity, long-term CAD and living in sparsely populated areas.