Affiliation:
1. I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russia (Sechenov University)
Abstract
The article discusses the prevention of gastrointestinal bleeding in critically ill patients who are hospitalized in intensive care units (ICU). The main factors contributing to the occurrence of GIB in such patients are considered. The leading place among them is occupied by a stay on artificial ventilation of the lungs for > 48 hours and blood coagulopathy. Patients at high risk of developing GIB need prophylactic administration of proton pump inhibitors, H2-blockers, sucralfate, which allows to prevent the occurrence of GIB and improve the prognosis of patients.
Publisher
Medical Informational Agency Publishers
Reference15 articles.
1. Spechler S.J. Peptic ulcer disease and its complications. In: Sleisenger and Fordtran’s Gastrointestinal and Liver Disease (Ed. Feldman M. et al.), 7th edition. 2002;1:747–781.
2. May A., Hahn E.G. Ulkus und Erosionen durch Streβ. In: Klinische Gastroenterologie (Hrsgb. Hahn E.G., Riemann J.F.). 3. Auflage, Thieme. 2000:763–767.
3. Plummer M.P., Blaser A.R., Deane A.M. Stress ulceration: prevalence, pathology and association with adverse outcomes. Crit. Care. 2014;18(2):213. DOI: 10.1186/cc13780
4. Buendgens L., Koch A., Tacke F. Prevention of stress-related ulcer bleeding at the intensive care unit: Risks and benefi ts of stress ulcer prophylaxis. World. J. Crit. Care Med. 2016;5(1):57–64. DOI: 10.5492/wjccm.v5.i1.57
5. Arnold C. Akute Ulkus (Stressulkus). In: Klinische Pathorhysiologie (Hrsgb. Siegenthaler W., Blum H.E.). Thieme, 9. Aufl age. 2006:811–812.