Сauses, risk factors, diagnostics and treatment of gastrointestinal bleeding in patients with a novel coronavirus infection (COVID-19)-Reference-Cited by-同舟云学术

Сauses, risk factors, diagnostics and treatment of gastrointestinal bleeding in patients with a novel coronavirus infection (COVID-19)

Published:2022-10-30 Issue:7-8 Volume:100 Page:341-345
ISSN:2412-1339
Container-title:Clinical Medicine (Russian Journal)
language:
Short-container-title:jour

Author:

Sheptulin A. A.¹^ORCID,Kardasheva S. S.¹^ORCID,Kurbatova A. A.¹^ORCID

Affiliation:

1. I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)

Abstract

The article discusses the pathogenetic and clinical aspects of gastrointestinal bleeding (GIB) in patients with a novel coronavirus infection (COVID-19). The possibility of direct interaction of the coronavirus with the receptors of the angiotensinconverting enzyme 2 (ACE-2) of the mucous membrane of the gastrointestinal tract with the development of its damage and subsequent bleeding has been shown. The value of anticoagulant therapy as a risk factor for the occurrence of GIB is evaluated inconsistently. In most patients with COVID-19 infection and GIB conservative hemostatic therapy is eff ective. The infl uence of GIB on the course and prognosis of a novel coronavirus infection has an contradictory interpretation. Given the lack of knowledge of the pathogenetic and clinical aspects of GIB in patients with COVID-19 infection, this problem requires further research.

Publisher

Medical Informational Agency Publishers

Subject

General Medicine

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