Platelet-rich plasma in the treatment of scleroatrophic lichen of the genitals

Abstract

The article provides comparative analysis of the current studies on the use of platelet-rich plasma (PRP) for the treatment of lichen sclerosus. The analysis includes 9 articles on efficiency of PRP in patients with genital lichen sclerosus. The article includes a listing of research and methods for evaluating the effect of therapy protocols. Most of the studies have shown a good therapeutic effect of the disease treatment with platelet-rich plasma. PRP may be used to quickly resolve subjective symptoms and reduce inflammation, as well as to treat synechia and cicatricial conditions. However, a problem concerning the mechanism of PRP, combined therapy with PRP, and topical steroids, has not been studied yet. It is necessary to conduct additional studies that will help to determine the number of procedures, and the interval between them. It is also necessary to develop criteria for evaluating the therapy effect, which includes histological examination.