Affiliation:
1. Military Medical Academy named after Kirov S.M. of the Ministry of Defense of Russia
2. Central Military Clinical Hospital named after Mandryka P.V. of the Ministry of Defense of Russia
Abstract
The article provides a review of specialized literature in order to generalize and systematize data on modern ideas about endometrioid disease in the clinical practice of doctors of various specialties. The social signifi cance of this disease is indicated. The article refl ects the main modern ideas about etiology and pathogenesis of endometriosis. Although there are a number of issues, they are not studied completely. The crucial role of the immune system malfunction in the formation of endometrioid disease is highlighted. The genetic ideas about the development of endometriosis are refl ected. Modern approaches to the treatment of endometriosis and the place of cholecalciferol in modern complex therapy of endometriosis are presented.
Publisher
Medical Informational Agency Publishers
Reference27 articles.
1. McKinnon B.D., Bertschi D., Bersinger N.A., Mueller M.D. Infl am mation and nerve fi ber interaction in endometriotic pain. Trends Endocrinol. Metab. 2015;26(1):1–10. DOI: 10.1016/j. tem.2014.10.003
2. Levkovich M.A., Ermolova N.V., Avanesova T.G., Markaryan I.V. Modern views on the pathogenesis of genital endometriosis: the role of hormonal, immunological, genetic factors. TMBV. 2017;2:2. (in Russian)
3. [El-Jefut M., Artymuk N.V. New about theories of pathogenesis of endometriosis. Fundamental and clinical medicine. 2019;3. (in Russian)
4. Farhat K.N., Savilova A.M., Makiyan Z.N., Adamyan L.V. Endometriosis: the role of stem cells in the development of the disease (literature review). Problems of reproduction. 2016;22(1):20–27. (in Russian)
5. Maignien C., Santulli P., Gayet V., Lafay-Pillet M.-C., Korb D., Bourdon M., Marcellin L., de Ziegler D., Chapron C. Prognostic Factors for Assisted Reproductive Technology in Women with Endometriosis-related Infertility. Am. J. Obstet. Gynecol. 2017;216(3):280. e1–280.e9.