Primary adrenal insufficiency-Reference-Cited by-同舟云学术

Primary adrenal insufficiency

Published:2024-06-02 Issue:3 Volume:102 Page:264-267
ISSN:2412-1339
Container-title:Clinical Medicine (Russian Journal)
language:
Short-container-title:jour

Author:

Kalenchits T. I.¹^ORCID,Kabak S. L.¹^ORCID,Didenko N. S.²,Glushko I. V.³

Affiliation:

1. Belarusian State Medical University

2. Bakoulev National Medical Research Center for Cardiovascular Surgery of the Ministry of Healthcare of Russia, Rehabilitation Сenter for Сhildren with Heart Defects

3. 6th City clinical hospital

Abstract

Due to the non-specificity of a number of clinical manifestations of Addison’s disease, the diagnosis of primary adrenal insuﬃciency in general therapeutic profile hospitals causes certain diﬃculties. The article presents a clinical case of diagnosing primary adrenal insuﬃciency in combination with autoimmune thyroiditis and hypogonadism as a manifestation of autoimmune polyglandular syndrome. Signs of Addison’s disease included hyperpigmentation of the skin and mucous membranes of the oral cavity, as well as low cortisol levels and an increase in adrenocorticotropic hormone(ACTH) concentration, detected in the blood serum antibodies to thyroperoxidase — a specific marker of autoimmune thyroid gland damage. A positive result of the test for autoantibodies to steroid-producing cells indicated functional ovarian insuﬃciency.

Publisher

Medical Informational Agency Publishers

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