THE POSSIBILITY OF USING GLIAL FIBRILLARY ACIDIC PROTEIN AS A BIOMARKER IN THE ACUTE PERIOD OF STROKE-Reference-Cited by-同舟云学术

THE POSSIBILITY OF USING GLIAL FIBRILLARY ACIDIC PROTEIN AS A BIOMARKER IN THE ACUTE PERIOD OF STROKE

Published:2019-10-29 Issue:4 Volume: Page:4-15
ISSN:2686-7192
Container-title:Russian neurological journal
language:
Short-container-title:РНЖ

Author:

Topuzova M. P.¹^ORCID,Alekseeva T. M.¹^ORCID,Panina E. B.¹^ORCID,Vavilova T. V.¹^ORCID,Portik O. A.¹^ORCID,Kovzelev P. D.¹^ORCID

Affiliation:

1. Federal State Budgetary Institution «Almazov National Medical Research Centre» of the Ministry of Health of the Russian Federation

Abstract

High mortality and disability resulting from a stroke throughout the world is the cause of fi nding new opportunities to improve early diagnosis and optimize therapeutic approaches. The article presents a review of the literature devoted to the study of glial fi brillary acidic protein (GFAP) as a biomarker in the acute period of stroke, which showed that its use is possible not only to diff erentiate the ischemic and hemorrhagic process, but also to determine the degree of destruction of brain tissue, as in the fi rst hours of a stroke, and in the dynamics. In addition, the GFAP analysis can be useful for monitoring the course of the disease, control the eff ectiveness of therapy, as well as to predict outcomes.

Publisher

Medical Informational Agency Publishers

Subject

Psychiatry and Mental health,Neurology (clinical),Neurology

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