Influence of UGT1A1 *6/*28 Polymorphisms on Irinotecan-Related Toxicity and Survival in Pediatric Patients with Relapsed/Refractory Solid Tumors Treated with the VIT Regimen
Author:
Publisher
Informa UK Limited
Subject
Pharmacology,Molecular Medicine
Reference41 articles.
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2. Glucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38), an Active Metabolite of Irinotecan (CPT-11), by Human UGT1A1 Variants, G71R, P229Q, and Y486D
3. Phase II Trial of Irinotecan in Children With Refractory Solid Tumors: A Children's Oncology Group Study
4. Irinotecan-induced toxicity pharmacogenetics: an umbrella review of systematic reviews and meta-analyses
5. UGT1A1 Promoter Genotype Correlates With SN-38 Pharmacokinetics, but Not Severe Toxicity in Patients Receiving Low-Dose Irinotecan
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1. Individual Irinotecan Therapy Under the Guidance of Pre-Treated UGT1A1*6 Genotyping in Gastric Cancer;Technology in Cancer Research & Treatment;2024-01
2. Importance of pharmacologic considerations in the development of targeted anticancer agents for children;Current Opinion in Pediatrics;2022-12-23
3. Combination chemotherapy consisting of irinotecan, etoposide, and carboplatin for refractory or relapsed neuroblastoma;Cancer Medicine;2022-03
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