Identification of a Class of WNK Isoform-Specific Inhibitors Through High-Throughput Screening-Reference-Cited by-同舟云学术

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Identification of a Class of WNK Isoform-Specific Inhibitors Through High-Throughput Screening

Published:2023-01 Issue: Volume:Volume 17 Page:93-105
ISSN:1177-8881
Container-title:Drug Design, Development and Therapy
language:en
Short-container-title:DDDT

Author:

Chlebowicz Julita^ORCID,Akella Radha^ORCID,Humphreys John M^ORCID,He Haixia^ORCID,Kannangara Ashari R,Wei Shuguang,Posner Bruce,Goldsmith Elizabeth J^ORCID

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmaceutical Science,Pharmacology

Reference34 articles.

1. WNK1, a Novel Mammalian Serine/Threonine Protein Kinase Lacking the Catalytic Lysine in Subdomain II

2. Phosphoregulation of the Na–K–2Cl and K–Cl cotransporters by the WNK kinases

3. Influence of WNK3 on intracellular chloride concentration and volume regulation in HEK293 cells

4. Evolutionarily conserved WNK and Ste20 kinases are essential for acute volume recovery and survival after hypertonic shrinkage in Caenorhabditis elegans

5. WNK1 is required for mitosis and abscission

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