Prevalence of carotid and femoral artery atherosclerosis among the Ivanovo Oblast population: data from the ATEROGEN-Ivanovo study

Author:

Ershova A. I.1ORCID,Balakhonova T. V.2ORCID,Meshkov A. N.1ORCID,Kutsenko V. A.1ORCID,Yarovaya E. B.1ORCID,Shalnova S. A.1ORCID,Lishchenko N. E.3ORCID,Novikova A. S.3ORCID,Aleksandrova E. L.3ORCID,Shutemova E. A.3ORCID,Belova O. A.3ORCID,Rachkova S. A.3ORCID,Boytsov S. A.1ORCID,Drapkina O. M.4ORCID

Affiliation:

1. National Medical Research Center of Cardiology; Moscow State University of Medicine and Dentistry

2. National Medical Research Center of Cardiology; I.M. Sechenov First Moscow State Medical University

3. Cardiology dispensary

4. National Medical Research Center for Therapy and Preventive Medicine

Abstract

Aim. To study the prevalence of carotid (CA) and femoral artery (FA) atherosclerosis among Russian population, mainly in middle age group, using a representative sample of one of the Central Russian regions.Material and methods. The analysis included participants of the ATEROGEN-Ivanovo study (sub-study of the ESSE-RF conducted in the Ivanovo region) aged 40-67 years, who were invited for CA and FA ultrasound to assess plaque presence. A total 1102 people were examined, which was >80% of the original sample.Results. The age of subjects was 54 [48; 60] years (men, 28%). Only 11,2% of participants took statins; 30,9% had low cardiovascular risk (CVR), 35,6% — moderate CVR, 21,8% — high CVR, and 11,8% — very high CVR. The incidence of at least one plaque in CA or FA was 73,6%. The prevalence of CA atherosclerosis was 76,4% in men and 59,1% in women, FA atherosclerosis — 54,9% and 28,3%, respectively. Furthermore, plaques were detected already at the age of 40. The incidence of plaques significantly increased with age, with the exception of carotid atherosclerosis in men, a significant increase in the incidence of which stopped at 45 years of age.Conclusion. Among the Ivanovo population aged 40-67 with a predominance of low-to-moderate CVR patients, there is a high prevalence of carotid and femoral atherosclerosis, which indicates a high potential for using ultrasound for diagnosing subclinical atherosclerosis in assessing CVR in people of this age range.

Publisher

Silicea - Poligraf, LLC

Subject

Cardiology and Cardiovascular Medicine

Reference16 articles.

1. Mach F, Baigent C, Catapano AL, et al. 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk. Eur Heart J. 2020;41(1):111-88. doi:10.1093/eurheartj/ehz455.

2. Diagnostics and correction of lipid metabolism disorders in order to prevent and treat of atherosclerosis Russian recommendations VII revision. Atherosclerosis and dyslipidemia. 2020;1(38):7-42. (In Russ.)

3. Thorsson B, Eiriksdottir G, Sigurdsson S, et al. Population distribution of traditional and the emerging cardiovascular risk factors carotid plaque and IMT: the REFINE-Reykjavik study with comparison with the Troms0 study. BMJ Open. 2018;8(5):e019385. doi:10.1136/bmjopen-2017-019385.

4. Meshkov AN, Boitsov SA, Ershova AI, et al. The ATHEROGEN-IVANOVO trial “Investigation of the specific features of the development and progression of ATHEROsclerosis at various sites, including those with a view to the GENetic and epigenetic cardiovascular risk factors — the ESSE-IVANOVO substudy” — design, bioinformation analysis algorithms, and exome sequencing results in pilot group patients. Profilakticheskaya Meditsina. 2013;16(6):11-20. (In Russ.)

5. Research organizing committee of the ESSE-RF project. Epidemiology of cardiovascular diseases in different regions of Russia (ESSE-RF). The rationale for and design of the study. Preventive medicine. 2013;16(6):25-34. (In Russ.)

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