RELATION OF ANTHROPOMETRIC INDEXES AND CORONARY HEART DISEASE

Author:

Shalnova S. A.1,Deev A. D.1,Muromtseva G. A.1,Balanova J. A.1,Imaeva A. E.1,Kapustina A. V.1,Evstifeeva S. E.1,Shepel R. N.1,Rotar O. P.2,Nedogoda S. V.3,Shabunova A. A.4,Chernykh T. M.5,Romanchuk S. V.6,Indukaeva E. V.7,Grinstein Y. I.8,Libis R. A.9,Duplyakov D. V.10,Trubacheva I. A.11,Efanov A. Y.12,Tolparov G. V.13,Kulakova N. V.14,Shlyakhto E. V.2,Boytsov S. A.15,Drapkina O. M.1

Affiliation:

1. National Medical Research Centre for Preventive Medicine

2. Almazov National Medical Research Centre

3. Volgograd State Medical University

4. Institute of Socio-Economic Development of Territories

5. Voronezh State Medical University

6. Ivanovo Regional Cardiology Clinic

7. Research Institute for Complex Issues of Cardiovascular Diseases under the Siberian Branch of the Russian Academy of Sciences

8. Krasnoyarsk State Medical University n.a. Prof. V. F. Voyno-Yasenetsky

9. Orenburg State Medical University

10. Samara Region Clinical Cardiology Hospital

11. Research Institute for Cardiology under the Siberian Branch of the Russian Academy of Medical Sciences

12. Tyumen State Medical University

13. North Ossetia State Medical Academy

14. Pacific State Medical University

15. National Medical Research Centre for Cardiology

Abstract

An epidemics of obesity in the world during recent two decades, has already led to increased prevalence of diabetes, metabolic syndrome, oncological diseases, etc. Obesity is assessed with a variety of indexes, and recently the number of such tools was added with the two additional: visceral obesity index (VOI) and index of lipid products deposition (ILPD). The aim of the study — evaluation of the relation of anthropometric parameters with coronary heart disease. Materials of the study were representative selections from 13 regions of the ESSE-RF trial. In analysis of associations of body mass index (BMI), waist circumference (WC), relation of WC to height (WC/height x 100), VOI and IPLD with correction on the age and region, it was found that all studied parameters are significantly correlated with ischemic heart disease, however when the main risk factors were added, only two remained — odds ratio (95% confidence interval) for: WC/height×100 — 1,030 (1,019;1,040) (р<0,0001) and VOI — 1,053 (1,020;1,087) (р<0,0015) in males and WC/height×100 — 1,027 (1,021;1,033) (р<0,0001) and VOI — 1,052 (1,022;1,083) (р<0,0007) in females. It is important to note almost identical values of odds ratio for the indexes in both sexes. Reliability of the models obtained is confirmed by ROC analysis, where the area under curve for males was 0,68 and for females 0,67. The results witness on legitimacy of search for novel parameters of obesity that would have good reproducibility and are also simple and easy to use.

Publisher

Silicea - Poligraf, LLC

Subject

Cardiology and Cardiovascular Medicine

Reference15 articles.

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