Clusters and components of the metabolic syndrome are associations with the prevalence of depression in open urban male population

Abstract

Aim. To establish associations of the frequency of detection of clusters and components of the metabolic syndrome (MS) with the prevalence of depression in open male population of moderately urbanized Siberian city.Material and methods. Cross-sectional epidemiological survey included 1000 individuals formed from the election list of males in one of the Tyumen administrative districts. The response rate was 85,0%. MS was assessed using the International Diabetes Federation (IDF) criteria. A self-administered WHO MONICA-psychosocial questionnaire was used to assess the levels of depression. Statistical analysis was conducted using a package of software program for medical data IBM SPSS Statistics 21.0.Results. In the open population of moderately urbanized Siberian city in men (age 25-64) with depression the following clusters of MS are prevalent: abdominal obesity (AO) + hypertriglyceridemia (HTG) + decrease of high-density lipoprotein cholesterol (hypoHDL-C) and AO + hypoHDL-C + arterial hypertension (AH); in the presence of a high level of depression AO + HTG + hypoHDL-C and AO + hypoHDL-C + AH are prevalent. A direct correlation was established between the prevalence of depression and abdominal obesity and hypertension, as well as the prevalence of a high level of depression with HTG and hypo-HDL cholesterol. In the open urban population in men (age 25-64) with high level of depression the following clusters of MS are prevalent: AO + HTG + hypoHDL-C and AO + HTG + hypoHDL-C + AH. We established an increase in the chances of developing a high level of depression with following MS clusters: AO + HTG + hypoHDL-C. According to IDF criteria, the prevalence of MS components in male population (age 25-64) in Tyumen was: AO — 42,6%; AH — 59,8%; hyperglycemia — 17,4%; HTG — 10,5%; hypoHDL-C — 4,6%. With a primary prevalence of MS components in men (age 25-64) with a low level of depression, the prevalence of HTG and hypoHDL-C in open population of moderately urbanized Siberian city prevails in men with high and mean levels of depression.Conclusion. The strategies for MS prevention in men of moderately urbanized city should contain measures to optimize nutrition regarding psychosocial determinants. This is due not only to the wide prevalence of overweight and obesity in Tyumen population but also to dyslipidemia associated with these factors.