POTENTIAL OF PHARMACOGENETICS IN THE CORRECTION OF ANTICOAGULANT THERAPY AMONG PATIENT WITH PROSTHETIC HEART VALVES

Author:

Zhuravleva I. Yu.1,Burkova T. V.2,Rutkovskaya N. V.2,Gorbunova E. V.2,Odarenko Yu. N.2,Savostiyanova Yu. Yu.2,Goncharova I. A.2

Affiliation:

1. ZAO NeoCor, Kemerovo

2. Research Institute of Complex Cardiovascular Problems, Siberian Branch, Russian Academy of Medical Sciences

Publisher

Silicea - Poligraf, LLC

Subject

Cardiology and Cardiovascular Medicine

Reference13 articles.

1. Antonov IM. Efficacy and safety of indirect anticoagulant warfarin when dosing, based on the results of pharmacogenetic testing. PhD Thesis. Candidate. Moscow 2009; 22 r. Russian (Antonov I. M. Effektivnost' i bezopasnost' primeneniya neprya- mogo antikoagulyanta varfarina pri ego dozirovanii, osnovan- nom na rezul'tatakh farmakogeneticheskogo testirovaniya. Avtoref diss kand med nauk. Moskva 2009; 22 s).

2. Kozlova TV. Monitoring of treatment with oral anticoagulants. Pharmatec 2003; 3: 87–92. Russian (Kozlova T. V. Kontrol' za lecheniem oral'ny- mi antikoagulyantami. Farmateka 2003; 3: 87–92).

3. Kropacheva ES, Panchenko EP. Anticoagulants of indirect action in a therapeutic clinic overview. Russian Medical Journal: an independent publication for doctors in 2009; 17 (8): 507–13. Russian (Kropacheva E. S., Panchenko E. P.. Antikoagulyanty nepryamogo deistviya v terapevtiche- skoi klinike: Obzor. Russkii meditsinskii zhurnal: nezavisimoe izdanie dlya praktikuyushchikh vrachei 2009; 17 (8): 507–13).

4. Sychev DA, Kropacheva ES, Ignat’ev IV, et al. Pharmacogenetics indirect anticoagulants: the importance of genotype in enhancing the effectiveness and safety of treatment. Cardiology 2006; 7: 72–8. Russian (Sychev D. A., Kropacheva E. S., Ignat'ev I. V. i dr. Farmakogenetika nepryamykh antikoagulyantov: znachenie genotipa v povyshenii effektivnosti i bezopasnosti terapii. Kardiologiya 2006; 7: 72–8).

5. Sychev DA, Antonov IM, Zagrebin SV, et al. Warfarin dosing algorithms, based on the results of pharmacogenetic testing: a real opportunity to optimize pharmacotherapy. Rational Pharmacotherapy in Cardiology 2007; 2: 59–66. Russian (Sychev D. A., Antonov I. M., Zagrebin S. V. i dr. Algoritmy dozirovaniya varfarina, osnovannye na rezul'tatakh far- makogeneticheskogo testirovaniya: real'naya vozmozhnost' optimiza- tsii farmakoterapii. Ratsional'naya Farmakoterapiya v Kardiologii 2007; 2: 59–66).

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