Cholestasis: algorithms for diagnosis and treatment

Author:

Polunina T. E.1ORCID

Affiliation:

1. A.I. Evdokimov Moscow State University of Medicine and Dentistry

Abstract

Recently, in the clinical practice of treating hepatobiliary diseases, significant progress has been made in understanding the molecular basis of bile formation and cholestasis pathophysiology. This article briefly summarizes the modern concepts of bile formation and cholestasis. The goals of drug therapy for cholestasis have been determined, which help to understand existing methods of treating cholestasis and contribute to the development of new agents for cholestatic liver diseases.

Publisher

Silicea - Poligraf, LLC

Reference21 articles.

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2. Yokoda RT, Rodriguez EA. Review: Pathogenesis of cholestatic liver diseases. World J Hepatol. 2020;12(8):423-35. doi:10.4254/wjh.v12.i8.423.

3. Polunina TE. Therapeutic approaches to the treatment of cholestatic liver diseases. Therapy. 2019;3:99-108. (In Russ.)

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5. Khungar V, Goldberg DS. Liver Transplantation for Cholestatic Liver Diseases in Adults. Clin Liver Dis. 2016;20:191-203. doi:10.1016/j.cld.2015.08.011.

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