Affiliation:
1. I.M. Sechenov First Moscow State Medical University; Scientific-Research Center of Comorbid Pathology “Rational Medicine”
2. Scientific-Research Center of Comorbid Pathology “Rational Medicine”
3. I.M. Sechenov First Moscow State Medical University
Abstract
This article focuses on the etiology and pathogenesis of nonvalvular atrial fibrillation in patients with comorbidities such as coronary artery disease, heart failure, type 2 diabetes, and chronic kidney disease. The authors discuss the interconnection of atrial fibrillation and these diseases, and also note the need for protection of such patients (prevention of cardioembolic stroke and other systemic embolism, reduction of coronary risk, improvement of prognosis, slowing the progression of renal dysfunction, increasing medical adherence, etc.) by adequate antithrombotic therapy that does not lose effectiveness and/or safety in presence of multiple diseases and polypharmacy.
Subject
Cardiology and Cardiovascular Medicine
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