Affiliation:
1. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University;
Regional Clinical Hospital
2. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University;
Federal Siberian Research Clinical Center
3. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University
4. Research Institute of Internal and Preventive Medicine — a branch of the Federal Research Center Institute of Cytology and Genetics
Abstract
The article presents a literature review on the study of the relationship of FGA, FGB, F2, F5, PAI, ITGA2 gene polymorphisms with the development of pulmonary embolism (PE). We concluded that genetic factors in the development of PE are to a greater extent mutations in the F2, F5, PAI, ITGA2 genes. There is a positive correlation between the presence of combined genetic mutations and the development of PE. The study of allelic polymorphism of hemostasis genes makes it possible to predict coagulation system disorders, including PE.
Subject
Cardiology and Cardiovascular Medicine
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