Key mechanisms of the relationship between vitamin D and cardiovascular disease

Abstract

Recent research indicates that vitamin D does indeed have a wide range of biological effects beyond its regulating function of bone and mineral homeostasis. Vitamin D deficiency is associated with leading predictors of cardiovascular risk, such as obesity, hypertension, and type 2 diabetes. In addition, it plays a role in the disease progression and worsening of the prognosis in patients with left ventricular hypertrophy, coronary artery disease, heart failure, and chronic kidney disease. An analysis was made of studies aimed at evaluating the efficacy and safety of vitamin D therapy in order to reduce the risk of cardiovascular pathologies, as well as improve the clinical course and outcomes in patients with existing metabolic disorders and cardiovascular diseases.