Some pro- and anti-inflammatory cytokines, their genetic polymorphism and postinfarct cardiac remodeling-Reference-Cited by-同舟云学术

Some pro- and anti-inflammatory cytokines, their genetic polymorphism and postinfarct cardiac remodeling

Published:2020-11-18 Issue:10 Volume:25 Page:4007
ISSN:2618-7620
Container-title:Russian Journal of Cardiology
language:
Short-container-title:Russ J Cardiol

Author:

Nikolaeva A. M.¹^ORCID,Babushkina N. P.²^ORCID,Ryabov V. V.³^ORCID

Affiliation:

1. Cardiology Research Institute, Tomsk National Research Medical Center

2. Research Institute of Medical Genetics, Tomsk National Research Medical Center

3. Cardiology Research Institute, Tomsk National Research Medical Center; National Research Tomsk State University; Siberian State Medical University

Abstract

The role of molecular genetic factors in cardiovascular disease (CVD) development has been actively studied in recent years. In patients with acute myocardial infarction and heart failure, the genetic component contributes to the determination of inflammation and persistence of inflammatory mediators in the myocardium. The genetic component in combination with traditional CVD risk factors determines the clinical course of the disease, the severity and its outcome. This review summarizes the data on relationship of proand anti-inflammatory cytokines with coronary artery disease and its clinical manifestations.

Publisher

Silicea - Poligraf, LLC

Subject

Cardiology and Cardiovascular Medicine

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