In vitro anticancer, antimicrobial and antiradical properties and bioactive compounds of endemic Wiedemannia orientalis Fisch. & Mey. flowers

Author:

KESER Serhat1ORCID,KESER Fatma1,TEKİN Suat2,TÜRKOĞLU İsmail1,KAYGILI Omer1ORCID,DEMİR Ersin3,YILMAZ Prof. Dr. Ökkeş1,SANDAL Süleyman2,KIRBAĞ Sevda1,KARATEPE Mustafa1ORCID

Affiliation:

1. FIRAT UNIVERSITY

2. INONU UNIVERSITY

3. DUZCE UNIVERSITY

Abstract

W. orientalis is a one-year herbaceous plant, located in the Lamiaceae family, and is called Ballıbaba in Turkish. In the presented study, the antimicrobial and anticancer properties of flowers extracts of endemic W. orientalis were investigated for the first time. Also, it was investigated the antiradical activity and phytochemical contents of this plant extracts. According to our study results, endemic W. orientalis flowers extract show very high anticancer activity against MCF-7, HCT-116 and LNCaP cancer cell lines, high antiradical activity against ABTS radicals, and effective antimicrobial activity against some microorganism caused infection in humans. In conclusion, endemic W. orientalis can be used as an anticancer and antimicrobial agent and this plant can be the subject of further studies in the field of herbal medicine.

Publisher

Journal of Physical Chemistry and Functional Materials

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