Role of surgery in multifocal glioblastoma
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Published:2022-03-03
Issue:3
Volume:72
Page:576
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ISSN:0030-9982
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Container-title:Journal of the Pakistan Medical Association
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language:
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Short-container-title:J Pak Med Assoc
Author:
Syeda Kubra Kishwar Jafri ,Syed Sarmad Bukhari ,Muhammad Shahzad Shamim
Abstract
The management of multifocal glioblastomas is a point of constant discussion amongst neuro-oncologists. Best outcomes in glioblastoma management come from gross total resection (GTR) followed by concomitant radiation and chemotherapy (CCRT). Multifocal disease is resistant to GTR. Conventional management of these lesion is usually biopsy only followed by CCRT. Recent evidence has shown that there may be some benefit to attempting GTR of the largest lesion whenever safe to do so.
Keywords: Glioblastoma multiforme; multifocal; radiotherapy; chemotherapy
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Publisher
Pakistan Medical Association