A METHOD FOR MORPHOMETRIC ASSESSMENT OF PATHOLOGICAL CONDITIONS OF THE RETINA AND CHOROID BASED ON SCANS OF OPTICAL COHERENCE TOMOGRAPHY OF THE EYE

Author:

Bondarenko Yu. F,Epikhin A. N,Epikhina Yu. N,Filippenko V. A,Dolgov V. V

Abstract

Optical coherence tomography (OCT) is a modern non-contact method of diagnostic examination which makes it possible to visualize a section of the retina as close as possible to its post-mortem histological section, and enables to distinguish individual layers of the human retina in a cross-section. The software pre-installed in such devices contains many different tools, but this is still not enough for a faster, more complete and accurate analysis of the obtained scans in order to make the correct diagnosis and choose the best treatment. There are more and more new and improved technologies for image processing in the world, which sets new tasks to develop additional software that can complement and expand the functionality of diagnostic equipment. This paper proposes a method of morphometric assessment of pathological conditions of the retina and chorioidea based on optical coherence tomography scans. This method is based on the algorithm for automated segmentation of the borders of the macular macular zone pathological focus, the algorithm for calculation of the area and volume of the pathological focus which together with other algorithms for analysis of the morphometric parameters of the human eye can be used for differential diagnostics of the pathological changes in the macular zone, for more precise diagnosis of the age-related macular degeneration (AMD) stage to prescribe a certain type and volume of treatment for stabilization and improvement of the central pontine visual functions.

Publisher

Volgograd State Medical University

Subject

Anesthesiology and Pain Medicine

Reference11 articles.

1. Global causes of blindness and distance vision impairment in 1990-2020: a systematic review and metaanalysis / S.R. Flaxman, R.R.A. Born, S. Resnickoff [et al.] // Lancet Glob. Health. 2017. Vol. 5, no. 12. P. e1221-e1234.

2. A large genomic association study of agerelated macular degeneration highlights the contribution of rare and common variants / L.G. Fritsche, W. Igl, J.N. Bailey [et al.] // Nat Genet. 2016. Vol. 48, no. 2. P. 134-143.

3. Wong W.L., Su H. Global prevalence of age-related yellow spot degeneration and disease burden projections for 2020 and 2040: a systematic review and metaanalysis // Lancet Planet Health. 2014. Vol. 2, no 2. P. 106-116.

4. Будзинская М.В., Погода Т.В., Генерозов Э.В. Влияние генетических мутаций на клиническую картину субретинальной неоваскуляризации. Сообщение 1. Роль полиморфизмов генов CFH и IL-8 // Вестник офтальмологии. 2011. Т. 127, № 4. С. 3-8.

5. Астахов Ю.С., Белехова С.Г. Толщина хориоидеи в норме и при возрастной макулярной дегенерации // Офтальмологические ведомости. 2014. Т. 7, № 1. С. 4-7.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3