Intravesical methods of treatment upon overactive bladder (literature review)

Abstract

In this article we come across generalized literature data devoted to treatment of overactive bladder (OAB). We look through basic methods of OAB treatment: application of M-cholinolythics and their disadvantages, BBC-therapy, and also intravesical methods. Intravesical methods like intravesical Oxibutanine electrophoresis, Capsaicyne and Rosipheranotoxine injections are not clinically widespread. However intravesical (intradetrusal) injections of Botulotoxine type A are used in an active way with nice clinical effects, but are demanding general anaesthesia with all it’s risks. The number of clinical trials devoted to Botulotoxine A intravesical usage via instillations is limited, thus demanding additional researches.