A Prooxidant and an Antioxidant Sow’s Status with Hepathopathy
Author:
Piatrouski Sergey1ORCID, Hlebus Natali2
Affiliation:
1. EI “Vitebsk state academy of veterinary medicine”, Vitebsk, Republic of Belarus 2. JV “PHARMLAND” LLC, Minsk Republic of Belarus
Abstract
The role of lipid peroxidation in the pathogenesis of liver diseases in sows was studied. The state of the antioxidant system in these diseases was also assessed. The liver of sows has been examined after slaughter. There were four groups formed: healthy, acute and chronic hepatosis (HS), and liver cirrhosis. An increase in the level of endogenous intoxication has established, the content of primary (diene conjugates), secondary (malondialdehyde, ketodienes, ketotrienes), and final (Schiff base) products of lipid peroxidation in the blood of sows with hepatopathy. Also noticed that sows with hepatopathy had decreased antioxidant protection, catalase activity, and concentration of tocopherol and ascorbic acid. The level of change was growing with a gravity of hepatopathy. The most expressed disturbance has been observed in sows with liver cirrhosis.
Publisher
Armenian National Agrarian University
Reference21 articles.
1. Abramov, S.S., Belko, A.A., Matsinovich, A.A.,Kurdeko, A.P., Kovalnok, Yu.K., Savateev, A.V.(2007). Lipid peroxidation and endogenousintoxication (importance in the pathogenesis of animaldiseases, ways of correction): monograph. Vitebsk: EEVSAVM, 208 (in Russian). 2. Balogh, K.W., Mária, H., Monika, K., Gyorgyi, M.M.(2012). Correlations between daily weight gain, lipidperoxidation and glutathione status of liver and kidneyin different pig genotypes. Archiv fur Tierzucht, 55,263-271. http://dx.doi.org/10.5194/aab-55-263-2012. 3. Baymurzaeva, A.A., Kelekhsaeva, V.G. (2023). Thestate of antioxidant protection and lipid peroxidationin acute viral hepatitis B. Research of young scientists:materials of the LV International. scientific conf.(Kazan, February 2023). Kazan, Young Scientist,4-11 (in Russian). https://moluch.ru/conf/stud/archive/480/17803/. 4. Boldyreva, Yu.V., Mardanov, Yu.M., Lebedev, I.A.,Alekhina, M.N., Zakharchuk, E.V., Adamchuk, S.V.(2021). Biochemical aspects of lipid peroxidation.Modern methods for diagnosing damage to cellmembranes. Bulletin of the Ural Medical AcademicScience, 18(2), 78–84 (in Russian). https://doi.org/10.22138/2500-0918-2021-18-2-78-84. 5. Erel, O. (2004). A novel automated method tomeasure total antioxidant response against potent freeradical reactions. Clin Biochem, 37, 112–119. https://doi:10.1016/j.clinbiochem.2003.10.014.
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