Association of the ACTN3 R577X polymorphism with glucose tolerance and gene expression of sarcomeric proteins in human skeletal muscle

Author:

Riedl Isabelle1,Osler Megan E.1,Benziane Boubacar2,Chibalin Alexander V.1,Zierath Juleen R.12

Affiliation:

1. Department of Molecular Medicine and Surgery; Section for Integrative Physiology; Karolinska Institutet; Stockholm Sweden

2. Department of Physiology and Pharmacology; Section for Integrative Physiology; Karolinska Institutet; Stockholm Sweden

Funder

The European Research Council Advanced Grant Ideas Program

Novo Nordisk Research Foundation

Swedish Research Council

Stockholm County Council

Swedish Foundation for Strategic Research

Swedish Diabetes Association

Lars Heirtas Minne

The Strategic Diabetes Program at Karolinska Institutet

Publisher

Wiley

Subject

Physiology (medical),Physiology

Reference35 articles.

1. Cloning and characterization of two human skeletal muscle alpha-actinin genes located on chromosomes 1 and 11;Beggs;J. Biol. Chem.,1992

2. A gene for speed: the emerging role of alpha-actinin-3 in muscle metabolism;Berman;Physiology (Bethesda),2010

3. The structure and function of alpha-actinin;Blanchard;J. Muscle Res. Cell Motil.,1989

4. The emerging genetics of type 2 diabetes;Bonnefond;Trends Mol. Med.,2010

5. Role of alpha-actinin-3 in contractile properties of human single muscle fibers: a case series study in paraplegics;Broos;PLoS ONE,2012

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