Hepatocytes maintain greater fluorescent bile acid accumulation and greater sensitivity to drug-induced cell death in three-dimensional matrix culture
Author:
Affiliation:
1. Department of Anatomy and Structural Biology; Division of Gastroenterology and Liver Diseases; Marion Bessin Liver Research Center; Albert Einstein College of Medicine; Montefiore Medical Center; Bronx New York
Funder
NIH
Publisher
Wiley
Subject
Physiology (medical),Physiology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.14814/phy2.12198/fullpdf
Reference54 articles.
1. Transcellular transport of fluorescein in hepatocyte monolayers: evidence for functional polarity of cells in culture;Barth;Proc. Natl Acad. Sci. USA,1982
2. Phenotypic stability of adult rat hepatocytes in primary monolayer culture;Bissell;Ann. N. Y. Acad. Sci.,1980
3. Isolated hepatocyte couplets and bile duct units-novel preparations for the in vitro study of bile secretory function;Boyer;Cell Biol. Toxicol.,1997
4. Hepatic transport systems regulating pHi, cell volume, and bile secretion;Boyer;Annu. Rev. Physiol.,1992
5. Toxicity and intracellular accumulation of bile acids in sandwich-cultured rat hepatocytes: role of glycine conjugates;Chatterjee;Toxicol. In Vitro,2014
Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Long-term human primary hepatocyte cultures in a microfluidic liver biochip show maintenance of mRNA levels and higher drug metabolism compared with Petri cultures;Biopharmaceutics & Drug Disposition;2016-07
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3