The anorexic hormone Peptide YY3-36is rapidly metabolized to inactive Peptide YY3-34in vivo-Reference-Cited by-同舟云学术

The anorexic hormone Peptide YY3-36is rapidly metabolized to inactive Peptide YY3-34in vivo

Published:2015-07 Issue:7 Volume:3 Page:e12455
ISSN:2051-817X
Container-title:Physiological Reports
language:en
Short-container-title:Physiol Rep

Author:

Toräng Signe¹,Veedfald Simon¹,Rosenkilde Mette Marie²,Hartmann Bolette¹,Holst Jens Juul¹

Affiliation:

1. NNF Center for Basic Metabolic Research and Department of Biomedical Sciences; Faculty of Health Sciences; University of Copenhagen; Copenhagen Denmark

2. Department of Neuroscience and Pharmacology; Faculty of Health Sciences; University of Copenhagen; Copenhagen Denmark

Funder

Novo Nordisk Center for Basic Metabolic Research (Novo Nordisk Foundation, Denmark)

Publisher

Wiley

Subject

Physiology (medical),Physiology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.14814/phy2.12455/fullpdf

Reference21 articles.

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2. Blockade of the neuropeptide Y Y2 receptor with the specific antagonist BIIE0246 attenuates the effect of endogenous and exogenous peptide YY(3-36) on food intake;Abbott;Brain Res.,1043

3. Kinetic Study of Neuropeptide Y (NPY) Proteolysis in Blood and Identification of NPY3-35: a new peptide generated by plasma kallikrein;Abid;J. Biol. Chem.,2009

4. A role for metalloendopeptidases in the breakdown of the gut hormone, PYY3-36;Addison;Endocrinology,2011

5. Human distribution and release of a putative new gut hormone, peptide YY;Adrian;Gastroenterology,1985

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