Spironolactone mitigates, but does not reverse, the progression of renal fibrosis in a transgenic hypertensive rat
Author:
Affiliation:
1. Department of Medicine University of Otago Dunedin New Zealand
2. Department of Medicine University of Melbourne Melbourne VIC Australia
3. Department of Pharmacology University of Otago Dunedin New Zealand
Funder
Maurice and Phyllis Paykel Trust
Otago Medical Research Foundation
Publisher
Wiley
Subject
Physiology (medical),Physiology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.14814/phy2.14448
Reference52 articles.
1. Regression of Existing Glomerulosclerosis by Inhibition of Aldosterone
2. Activation of Thiazide-Sensitive Co-Transport by Angiotensin II in the cyp1a1-Ren2 Hypertensive Rat
3. Transgenic Animals in Cardiovascular Disease Research
4. Long-term use of low-dose spironolactone in spontaneously hypertensive rats: Effects on left ventricular hypertrophy and stiffness
5. Spironolactone prevents chronic kidney disease caused by ischemic acute kidney injury
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