Effect of apical chloride concentration on the measurement of responses to CFTR modulation in airway epithelia cultured from nasal brushings
Author:
Affiliation:
1. Department of Pediatrics National Jewish Health Denver CO USA
2. Department of Pediatrics Anschutz Medical Center University of Colorado Denver Aurora CO USA
3. Dept. of Internal Medicine University of Iowa Iowa City IA USA
Funder
Cystic Fibrosis Foundation
Publisher
Wiley
Subject
Physiology (medical),Physiology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.14814/phy2.14603
Reference66 articles.
1. Effect of VX-770 in Persons with Cystic Fibrosis and the G551D-CFTRMutation
2. Positive clinical response to ivacaftor treatment in an individual with the CFTR genotype F508del/V456A;Bratcher P. E.;Journal of Cystic Fibrosis,2019
3. In Vivo Airway Surface Liquid Cl− Analysis with Solid-State Electrodes
4. NHERF1 and CFTR restore tight junction organisation and function in cystic fibrosis airway epithelial cells: role of ezrin and the RhoA/ROCK pathway
5. Loss of Anion Transport without Increased Sodium Absorption Characterizes Newborn Porcine Cystic Fibrosis Airway Epithelia
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1. Net benefit of ivacaftor during prolonged tezacaftor/elexacaftor exposure in vitro;Journal of Cystic Fibrosis;2022-07
2. Increased intracellular Cl− concentration mediates neutrophil extracellular traps formation in atherosclerotic cardiovascular diseases;Acta Pharmacologica Sinica;2022-05-05
3. Receptor-mediated activation of CFTR via prostaglandin signaling pathways in the airway;American Journal of Physiology-Lung Cellular and Molecular Physiology;2022-03-01
4. Measurements of spontaneous CFTR-mediated ion transport without acute channel activation in airway epithelial cultures after modulator exposure;Scientific Reports;2021-11-19
5. Elexacaftor is a CFTR potentiator and acts synergistically with ivacaftor during acute and chronic treatment;Scientific Reports;2021-10-06
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