Impact of environmental air pollution on respiratory health and function

Author:

Wallbanks Samuel1,Griffiths Benjamin2,Thomas Maximillian3,Price Oliver J.24,Sylvester Karl P.56ORCID

Affiliation:

1. Birmingham Heartlands Hospital University Hospitals Birmingham Birmingham UK

2. School of Biomedical Sciences, Faculty of Biological Sciences University of Leeds Leeds UK

3. Respiratory Physiology University Hospitals Sussex NHS Foundation Trust Brighton UK

4. Department of Respiratory Medicine Leeds Teaching Hospitals NHS Trust Leeds UK

5. Respiratory Physiology Papworth Hospital NHS Foundation Trust Cambridge UK

6. Respiratory Physiology Cambridge University Hospitals NHS Foundation Trust Cambridge UK

Abstract

AbstractEnvironmental air pollution presents a considerable risk to global respiratory health. If critical levels are exceeded, inhaled pollutants can lead to the development of respiratory dysfunction and provoke exacerbation in those with pre‐existing chronic respiratory disease. Over 90% of the global population currently reside in areas where environmental air pollution is considered excessive—with adverse effects ranging from acute airway irritation to complex immunomodulatory alterations. This narrative review provides an up‐to‐date perspective concerning the impact of environmental air pollution on respiratory health and function and describes the underpinning mechanisms that contribute to the development and progression of chronic respiratory disease.

Publisher

Wiley

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