Capturing the multifactorial nature of ARDS - “Two-hit” approach to model murine acute lung injury

Author:

Hoegl Sandra12,Burns Nana3,Angulo Martín4,Francis Daniel5,Osborne Christopher M.3,Mills Tingting W.6,Blackburn Michael R.6,Eltzschig Holger K.1,Vohwinkel Christine U.13

Affiliation:

1. Organ Protection Program; School of Medicine; Department of Anesthesiology; University of Colorado; Aurora Colorado

2. Developmental Lung Biology; Cardio Vascular Pulmonary Research Laboratories; Division of Pulmonary Sciences and Critical Care Medicine; Division of Pediatric Critical Care; Departments of Medicine and Pediatrics; University of Colorado; Anschutz Medical Campus; Aurora Colorado

3. Feinberg School of Medicine; Division of Pulmonary and Critical Care; Northwestern University; Chicago Illinois

4. Department of Respiratory Therapy; Colorado Children's Hospital; Aurora Colorado

5. Department of Biochemistry and Molecular Biology; University of Texas Health Science Center Houston; Houston Texas

6. Department of Anesthesiology; University Hospital of Ludwig-Maximilians-University; Munich Germany

Publisher

Wiley

Subject

Physiology (medical),Physiology

Reference50 articles.

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2. Simvastatin decreases hyperoxic oxygen-induced acute lung injury by upregulating eNOS;Bao;Am. J. Physiol. Lung Cell. Mol. Physiol.,2017

3. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome;Brower;N. Engl. J. Med.,2000

4. Health evaluation of experimental laboratory mice;Burkholder;Curr. Protoc. Mouse Biol.,2012

5. Enhanced innate inflammation induced by anti-BTLA antibody in dual insult model of hemorrhagic shock/sepsis;Cheng;Shock,2016

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