P2X7 receptor antagonism ameliorates renal dysfunction in a rat model of sepsis-Reference-Cited by-同舟云学术

P2X7 receptor antagonism ameliorates renal dysfunction in a rat model of sepsis

Published:2018-02-27 Issue:5 Volume:6 Page:e13622
ISSN:2051-817X
Container-title:Physiological Reports
language:en
Short-container-title:Physiol Rep

Author:

Arulkumaran Nishkantha¹²³,Sixma Marije L.¹,Pollen Sean¹,Ceravola Elias¹,Jentho Elisa¹,Prendecki Maria³,Bass Paul S.²⁴,Tam Frederick. W. K.³,Unwin Robert J.²,Singer Mervyn¹

Affiliation:

1. Bloomsbury Institute of Intensive Care Medicine; University College London; London United Kingdom

2. Division of Medicine; Department of Nephrology; University College London; London United Kingdom

3. Imperial College Renal and Transplant Centre; Hammersmith Hospital; London United Kingdom

4. Department of cellular pathology; Royal Free hospital; London United Kingdom

Funder

Wellcome Trust

Clinical Research Training Fellowship

Diamond Fund from Imperial College Healthcare Charity

Ken and Mary Minton Chair of Renal Medicine

Publisher

Wiley

Subject

Physiology (medical),Physiology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.14814/phy2.13622/fullpdf

Reference37 articles.

1. Basal activation of the P2X7 ATP receptor elevates mitochondrial calcium and potential, increases cellular ATP levels, and promotes serum-independent growth;Adinolfi;Mol. Biol. Cell,2005

2. Expression of the P2X7 receptor increases the Ca2 + content of the endoplasmic reticulum, activates NFATc1, and protects from apoptosis;Adinolfi;J. Biol. Chem.,2009

3. Dimethyl sulfoxide inhibits NLRP3 inflammasome activation;Ahn;Immunobiology,2014a

4. Methylsulfonylmethane inhibits NLRP3 inflammasome activation;Ahn;Cytokine,2014b

5. Extracellular ATP and ADP activate transcription factor NF-kappa B and induce endothelial cell apoptosis;Albertini;Biochem. Biophys. Res. Commun.,1998

Cited by 21 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Role of G protein coupled receptors in acute kidney injury;Cell Communication and Signaling;2024-09-02

2. Alkaline phosphatase treatment of acute kidney injury—an update;Nephrology Dialysis Transplantation;2024-02-23

3. Inflammasome modulation with P2X7 inhibitor A438079-loaded dressings for diabetic wound healing;Frontiers in Immunology;2024-02-15

4. Restoration of the Mucosal IgA Response by Improving CD4+ T Pyroptosis Fails to Attenuate Gut Bacterial Translocation and Organ Damage After LPS Attack;Digestive Diseases and Sciences;2024-02-09

5. Molecular insights into P2X signalling cascades in acute kidney injury;Purinergic Signalling;2024-01-22