Airway delivery of interferon-γoverexpressing macrophages confers resistance toMycobacterium aviuminfection in SCID mice

Author:

Pasula Rajamouli1,Britigan Bradley E.234,Kesavalu Banurekha1,Abdalla Maher Y.24,Martin William J.5

Affiliation:

1. Department of Internal Medicine; University of Cincinnati College of Medicine; Cincinnati Ohio

2. Research Service; VA Medical Center - Nebraska/Western Iowa; Omaha Nebraska

3. Department of Internal Medicine and Microbiology and Immunology; University of Nebraska Medical Center; Omaha Nebraska

4. Department of Pathology and Microbiology; College of Medicine; University of Nebraska Medical Center; Omaha Nebraska

5. College of Public Health; The Ohio State University; Columbus Ohio

Funder

National Institutes of Health

U.S. Department of Veterans Affairs

National Institute of Environmental Health Sciences

Publisher

Wiley

Subject

Physiology (medical),Physiology

Reference80 articles.

1. Effector mechanisms involved in cytokine-mediated bacteriostasis of Mycobacterium avium infections in murine macrophages;Appelberg;Immunology,1993

2. Role of gamma interferon and tumor necrosis factor alpha during T-cell-independent and -dependent phases of Mycobacterium avium infection;Appelberg;Infect. Immun.,1994

3. Armstrong , M. Y. M. T. Cushion 1994 Animal models

4. Cutaneous infections due to nontuberculous mycobacteria: histopathological review of 28 cases. Comparative study between lesions observed in immunosuppressed patients and normal hosts;Bartralot;J. Cutan. Pathol.,2000

5. Secretion of cytokines by human macrophages upon infection by pathogenic and non-pathogenic mycobacteria;Beltan;Microb. Pathog.,2000

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