Alterations in fatty acid metabolism and sirtuin signaling characterize early type-2 diabetic hearts of fructose-fed rats-Reference-Cited by-同舟云学术

Alterations in fatty acid metabolism and sirtuin signaling characterize early type-2 diabetic hearts of fructose-fed rats

Published:2017-08 Issue:16 Volume:5 Page:e13388
ISSN:2051-817X
Container-title:Physiological Reports
language:en
Short-container-title:Physiol Rep

Author:

Lou Phing-How¹,Lucchinetti Eliana²,Scott Katrina Y.¹,Huang Yiming¹,Gandhi Manoj¹,Hersberger Martin³,Clanachan Alexander S.¹,Lemieux Hélène⁴,Zaugg Michael¹²

Affiliation:

1. Department of Pharmacology; University of Alberta; Edmonton Alberta Canada

2. Department of Anesthesiology and Pain Medicine; University of Alberta; Edmonton Alberta Canada

3. Division of Clinical Chemistry and Biochemistry; University Children's Hospital Zürich; Zurich Switzerland

4. Faculty Saint-Jean; University of Alberta; Edmonton Alberta Canada

Funder

Natural Sciences and Engineering Research Council of Canada

Heart and Stroke Foundation of Canada

Canadian Institutes of Health Research

Genome British Columbia

Genome Canada

Publisher

Wiley

Subject

Physiology (medical),Physiology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.14814/phy2.13388/fullpdf

Reference87 articles.

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3. Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling;Alrob;Cardiovasc. Res.,2014

4. Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart;Anderson;J. Am. Coll. Cardiol.,2009a

5. Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans;Anderson;J Clin Invest,2009b

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