A1899, PK-THPP, ML365, and Doxapram inhibit endogenous TASK channels and excite calcium signaling in carotid body type-1 cells
Author:
Affiliation:
1. Department of Physiology, Anatomy and Genetics; University of Oxford; Oxford United Kingdom
2. Nuffield Department of Anaesthetics; Oxford University Hospitals; Oxford United Kingdom
Funder
Difficult Airway Society
National Institute of Academic Anaesthesia
Medical Research Council
Publisher
Wiley
Subject
Physiology (medical),Physiology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.14814/phy2.13876/fullpdf
Reference45 articles.
1. Doxapram stimulates dopamine release from the intact rat carotid body in vitro;Anderson Beck;Neurosci. Lett.,1995
2. A novel oxygen-sensitive potassium current in rat carotid body type I cells;Buckler;J. Physiol.,1997
3. TASK-like potassium channels and oxygen sensing in the carotid body;Buckler;Respir. Physiol. Neurobiol.,2007
4. Effects of exogenous hydrogen sulphide on calcium signalling, background (TASK) K channel activity and mitochondrial function in chemoreceptor cells;Buckler;Pflugers Arch.,2012
5. TASK channels in arterial chemoreceptors and their role in oxygen and acid sensing;Buckler;Pflugers Arch.,2015
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