Glucagon-like peptide-1 receptor antagonism impairs basal exercise capacity and vascular adaptation to aerobic exercise training in rats

Author:

Scalzo Rebecca L.1ORCID,Knaub Leslie A.1,Hull Sara E.1,Keller Amy C.12,Hunter Kendall3,Walker Lori A.4,Reusch Jane E. B.12

Affiliation:

1. Division of Endocrinology; University of Colorado School of Medicine; Aurora Colorado

2. Department of Medicine; Denver VA Medical Center; University of Colorado School of Medicine; Aurora Colorado

3. Division of Bioengineering; University of Colorado School of Medicine; Aurora Colorado

4. Division of Cardiology; University of Colorado School of Medicine; Aurora Colorado

Funder

AstraZeneca

National Institutes of Health

Denver Research Institute

Center for Women's Health Research

Publisher

Wiley

Subject

Physiology (medical),Physiology

Reference39 articles.

1. The glucagon-like peptide-1 receptor regulates endogenous glucose production and muscle glucose uptake independent of its incretin action;Ayala;Endocrinology,2009

2. Isoform switching from SM-B to SM-A myosin results in decreased contractility and altered expression of thin filament regulatory proteins;Babu;AJP,2004

3. Skeletal muscle deoxygenation after the onset of moderate exercise suggests slowed microvascular blood flow kinetics in type 2 diabetes;Bauer;Diabetes Care,2007

4. Cardiopulmonary dysfunction and adiponectin in adolescents with type 2 diabetes;Bjornstad;J. Am. Heart Assoc.,2016

5. Postprandial hyperglycaemia and cardiovascular complications of diabetes: an update;Ceriello;Nutr. Metab. Cardiovasc. Dis.,2006

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