COMPONENTS OF ARTEMISIA SOGDIANA

Abstract

Phytochemical research and effective use of medicinal flora in the future create the basis for the development of the domestic pharmaceutical industry and allow not only to fill the deficit of drugs, but also contribute to the development of new, environmentally friendly and a number of qualities of unique, export-oriented preparations. The plants of the genus Artemisia L. are rich sources of biologically active secondary metabolites. Phytochemical study of secondary metabolites of plants of the genus Artemisia has led to the creation on their basis, in particular, on the sesquiterpene lactones, antitumor (Artemisinin and its derivatives; Arglabin), antiatherosclerotic (Leucomisin (preparation Oligvon)), cardiotonic (Tauremisin), anthelmintic (α-Santonin) and antimalarial (Artemisinin and its derivatives) preparations. In order to search for natural biologically active compounds, we studied the components of the alcohol extract of the aerial part of Artemisia sogdiana Bunge, collected during budding in the Zaamin district of the Jizzakh region of Uzbekistan. The result of phytochemical research for the first time from this plant is isolated a phenolic compound xanthoxylin, sesquiterpene lactone artesin, flavonoids genkwanin and eupatilin, the structure of which is established on the basis of spectral data.